Table 2 The density (ρ), and apparent molar volume (\({V_\varphi }\)), of GBP in aqueous Betaine, DES, and betaine octyl ester chloride in 0.01,0.03,0.05 molality concentration under 298 K.

From: Gabapentin drug interactions in water and aqueous solutions of green betaine based compounds through volumetric, viscometric and interfacial properties

amsolvent (mol kg−1)

0.0102

0.0306

0.0498

Betaine

bmsolution

(mol kg−1)

10−3 ρ

(kg cm−3)

10−6 Vφ

(m3 mol−1)

bmsolution

(mol kg−1)

10−3 ρ

(kg cm−3)

10−6 Vφ

(m3 mol−1)

bmsolution

(mol kg−1)

10−3 ρ

(kg cm−3)

10−6 Vφ

(m3 mol−1)

0.0000

0.99819

-

0.0000

0.99870

-

0.0000

0.99900

-

0.0010

0.99822

138.747

0.0010

0.99870

141.474

0.001

0.99903

141.193

0.0049

0.99834

140.697

0.0049

0.99881

142.774

0.005

0.99914

143.212

0.0100

0.99850

140.154

0.0099

0.99896

142.115

0.0097

0.99927

143.491

0.0201

0.99880

140.851

0.0204

0.99926

142.372

0.02

0.99957

142.774

0.0293

0.99907

141.21

0.0298

0.99953

142.427

0.0294

0.99983

143.048

DES (Betaine: Urea 1:2)

0.0000

0.99799

-

0.0000

0.99897

-

0.0000

1.00005

-

0.0019

0.99817

140.862

0.0010

0.99901

142.559

0.0010

1.00009

142.356

0.0050

0.99846

142.837

0.0050

0.99917

142.225

0.0050

1.00025

142.379

0.0100

0.99894

142.676

0.0099

0.99936

142.777

0.0099

1.00043

143.470

0.0200

0.99987

143.13

0.0200

0.99975

143.141

0.0193

1.00079

143.504

0.0295

1.00075

143.448

0.0296

1.0001

143.644

0.0298

1.00117

143.911

IL (betaine octyl ester chloride)

0.0000

0.99896

-

0.0000

0.99961

-

0.0000

1.00007

-

0.0010

0.99899

140.271

0.0010

0.99964

140.274

0.0010

1.00010

140.790

0.0050

0.99911

141.349

0.0049

0.99975

142.776

0.0049

1.00021

142.518

0.0099

0.99926

141.155

0.0099

0.99989

142.913

0.0100

1.00034

144.090

0.0198

0.99955

141.527

0.0203

1.00018

143.115

0.0199

1.00062

143.493

0.0301

0.99984

141.905

0.0299

1.00044

143.396

0.0289

1.00085

144.151

  1. The standard uncertainties for molality, temperature and pressure were u (m) = 0.001 mol kg−1, u (T) = 0.2 K, u (P) = 10.5 hPa, respectively with level of confidence 0.95. The standard combined uncertainty for density and apparent molar volume were about, uc (ρ) = 0.06 × 10−3 g cm−3 and uc(Vφ) = 5 × 10−5m5 mol−1 (level of confidence 0.68), respectively. aThe molality of the prepared betaine compound in water (solvent). bThe molality of the prepared gabapentin in aqueous betaine-based compounds.