Table 5 Comparison of relative intensities of metabolomics between AML patients after treatment (remission/non-remission).

From: Role of metabolomic changes in diagnosis and assessment of treatment response in acute myeloid leukemia

Variable

Remission mean

Remission SD

Non-remission mean

Non-remission SD

p-value

Cholesterol

19.74

15.03

25

9.07

0.11

Lipids

34.87

17.73

44.79

9.45

0.01

Leucine

22.34

14.91

26.23

6.44

0.19

Isoleucine

20.24

13.77

23.62

5.47

0.22

Valine

18.98

9.82

23.27

5.26

0.14

Hydroxybutarate

65.38

30.07

85.62

16.29

0.02

Lactate

20.15

10.44

25.34

9.89

0.12

Alanine

19.08

9.4

25.17

9.1

0.02

Adipic Acid

20.65

10.34

27.1

10.01

0.03

Arginine

15.12

7.13

20.64

10.52

0.04

Lysine

13.82

6.96

17.66

10.17

0.15

Acetate

12.96

5.81

16.58

8.82

0.11

Glutamate

23.82

9.68

31.67

9.79

0.01

Glutamine

14.71

7.03

22.61

13.48

0.01

Ketoglutarate

14.19

6.72

19.33

10.79

0.01

Citrate

12.19

5.11

19.15

9.11

0.00

Albumin

11.84

5.13

15.73

9.1

0.06

Creatine

8.53

3.98

10.91

8.83

0.18

Choline

15.34

5.03

22.24

14.25

0.01

Glucose

8.45

3.41

8.13

6.41

0.81

TMAO

9.11

3.95

7.46

7.28

0.28

Proline

15.39

5.14

13.36

9.43

0.30

Glycine

10.33

5.83

8.64

5.87

0.27

Glycerol

11.21

7.06

12.01

4.37

0.60

Myoinositol

13.45

4.45

13.2

6.93

0.87

Citruline

15.25

5.11

15.66

7.38

0.80

Ornithine

15.91

7.86

15.53

5.32

0.83

Methionine

16.11

4.89

17.6

6.64

0.33

Glycoproteins

19.03

6.69

23.89

10.92

0.07

Serine

17.41

5.67

24.46

13.8

0.00

Creatinine

15.34

5.03

20.09

14.25

0.09

Threonine

16.3

5.59

22.15

16.52

0.00

B_Glucose

14.32

5.67

21.16

19.48

0.07

Pyrovate

11.99

5.75

18.6

21.11

0.10

Glycerol lipids

10.93

5.77

16.94

21.23

0.14

Alpha glucose

16.65

23.05

10.64

6.28

0.17

Tyrosine

5.2

3.26

3.67

6.68

0.26

Histidine

2.55

3.1

2.01

1.73

0.41

Tryptophan

1.16

2.88

1.69

1.53

0.38

Methy histidine

0.53

1.5

1.25

1.41

0.61

Formate

0.46

0.47

0.83

0.97

0.07

  1. p-value ≤ 0.05 is considered statistically significant.