Fig. 1
From: Revealing the role of U2AF1 in splicing regulation and chimeric RNA dynamics
U2AF1 expression profile in different cancers. (A) Data from the cBioPortal representing the expression of U2AF1 in different cancer types based on structural variant data, mutation data, and copy number alteration (CNA). (B) Structure of U2AF1 genes with RNA recognition motif (RRM) domain and two zinc-finger domains where the common S34F/Y mutation occurs. (C) Data from cBioPortal represents the probability of overall survival in altered and unaltered groups, with altered groups having low overall survival35.
