Table 1 Summary points.
From: Two paired HPV-59 cervical cancer cell lines with distinct chemoradioresistant phenotypes
Characteristic | AdMer35 | AdMer43 |
|---|---|---|
HPV status | HPV 59 | HPV 59 |
Immunophenotypic characterization | cytokeratin+fibronektin− | cytokeratin+fibronektin− |
Chromosome analysis | near-tetraploid | near-triploid |
Proliferation potential in vitro | +1 | +++1 |
Ki67 expression | Ki67+ | Ki67+ |
Migration potential (time for 100% to migrate) | 32h2 | > 50h2 (not achieved) |
Tumorigenicity in mice | + | + |
Radio sensitivity | yes | no |
Chemosensitivity, IC503 | ||
Paclitaxel | 3.0 nM | 7.3nM |
Carboplatin | 54.3 nM | 87.8 nM |
Tumorsphere formation | + | + |
