Fig. 8 | Scientific Reports

Fig. 8

From: Ameliorative effects of gum Arabic–coated selenium nanoparticles on Cisplatin-induced cerebellar neurotoxicity in rats

Fig. 8

Effect of Cis and/or AG. SeNPs. on the immuno-expressional level of GFAP protein in rat cerebellar tissue of different groups. (A) Control and (B) AG. SeNPs. groups showed neural filaments and small astrocytes with short processes and a mild brown stain in the granular and molecular layers. (C): Cis group showed significant GFAP upregulation in different cerebellar layers. (D) AG. SeNPs. + Cis cotreatment significantly reduces GFAP expression (arrowheads). (E) GFAP labeling index; Data are expressed as mean ± S.E. (n = 6). ****Significant change at P < 0.0001. Scale bar: 50 μm.

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