Fig. 9 | Scientific Reports

Fig. 9

From: Ameliorative effects of gum Arabic–coated selenium nanoparticles on Cisplatin-induced cerebellar neurotoxicity in rats

Fig. 9

Effect of Cis and/or AG. SeNPs. on the immuno-expressional level of NFL protein in male rat cerebellar tissue of different groups. (A): The Control and (B) AG. SeNPs. treated animals exhibit normal NFL expressions in Purkinje cells and molecular layers. (C) cisplatin administered animals show marked NFL intensity downregulation in the Purkinje cell layer. (D) AG. SeNPs. treatment further enhances NFL expression in combining group. (E) NFL labeling index; Data are expressed as mean ± S.E. (n=6). **, ***, **** Significant change at P < 0.01, P < 0.001, P < 0.0001 respectively. (arrowheads). Scale bar: 50 µm.

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