Fig. 2 | Scientific Reports

Fig. 2

From: INHBA: a mitochondrial-related pan-cell death gene associated with the prognosis and immunity of OSCC

Fig. 2

Screening of major cell types and mitochondria-associated pan-cell death genes (MAPGs) in OSCC. (A) UMAP visualization of major cell types. (B) UMAP plots contrasting normal and malignant cells in OSCC. (C) Bar graph depicting the relative proportions of cell types. (D) Marker genes expressed within the four major cell compartments. (E) Scores of OSCC related to mitochondrial and cell death processes in normal and malignant cells. (F) Volcano plot illustrating differentially expressed mitochondria-related genes (MIGs) in OSCC. (G) Volcano plot showing differentially expressed pan-cell death-related genes (PCDGs) in OSCC. (H) Correlation analysis between MIGs and PCDGs. (I) The gene functional enrichment analysis (GO and KEGG analysis). (J) Univariate Cox regression analysis identifying 19 MAPGs significantly associated with prognosis. (K) Expression levels of MAPGs in normal group and HNSCC group. GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

Back to article page