Fig. 3 | Scientific Reports

Fig. 3

From: INHBA: a mitochondrial-related pan-cell death gene associated with the prognosis and immunity of OSCC

Fig. 3

Analysis of OSCC subtypes based on MAPGs. (A) Two MAPGs-related molecular clusters were identified by NMF cluster analysis. (B) PCA analysis of distinct MAPGs-related molecular clusters. (C) Kaplan-Meier curve of differential survival between C1 and C2 groups. (D) Heatmap of the relationship between ESTIMATE scores, GSVA, and different cohorts of the two clusters. (E–G) Differences in the expression of immune infiltrating cells and immune related functions based on ssGSEA and CIBERSORT between the two clusters. (H) Expression differences of chemokine related genes between the two clusters. (I) Expression differences of immune checkpoint related genes between the two clusters. (K–M) ESTIMATEcore, StromalScore and TumorPurity for two clusters. (N) Volcano plot showing differentially expressed MAPGs in OSCC. (O,P) GO and KEGG enrichment analysis. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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