Fig. 7 | Scientific Reports

Fig. 7

From: INHBA: a mitochondrial-related pan-cell death gene associated with the prognosis and immunity of OSCC

Fig. 7

Downstream exploration of fibroblast subsets. (A) UMAP plots for fibroblast subsets in normal and tumor tissues, and bar graph of relative cell proportions. (B) Marker genes expressed in 4 major cell compartments. (C,D) The relationship of INHBA expression and different cell clusters in normal and tumor tissues. (E) Correlation analysis of POSTN and TAGLN with INHBA. (F,I) Strength and number of ligand-receptor interactions between pairs of cell populations in the normal (F) and OSCC (I) groups based on CellChat analysis. (G,J) Bubble plot of several tumor-specific pathways among different cell clusters in normal (G) and tumor (J) tissues. (H) PTN signaling network shown via heatmap, violin plot, and circle plot in normal tissues. (K-L) MIF and POSTN signaling network shown via heatmap, violin plot and circle plot in tumor tissues. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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