Fig. 8 | Scientific Reports

Fig. 8

From: INHBA: a mitochondrial-related pan-cell death gene associated with the prognosis and immunity of OSCC

Fig. 8

Clinical transformation of INHBA in OSCC. (A–D) Kaplan-Meier curves showing the relationship between INHBA expression and survival in the OSCC immunotherapy cohorts. (E) Relationship between INHBA expression and cetuximab treatment. (F,I) Plot of correlation analysis between INHBA expression and several drug sensitivities (IC50) in two databases: GDSC and PRISM. A positive correlation is represented in blue, indicating that increased gene expression corresponds to greater drug sensitivity, whereas red indicates the contrary. (G) Relationship between INHBA expression and selumetinib sensitivity. (J) Relationship between INHBA expression and naltrexone sensitivity. (H, K) Molecular docking structure diagram of INHBA and two drugs with the highest binding affinities. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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