Table 9 Antitumor activity of the essential oils of P. graveolens L., M. longifolia L., and C. frutescens L. plants exposed to salinity for 2 months against human hepatocellular cancer cell line (HepG2) and human colorectal carcinoma (HCT-116) (IC50 µg/ml).
Plant name | Salinity levels (mM NaCl) | HepG2 (IC50 µg/ml) | HCT-116 (IC50 µg/ml) |
|---|---|---|---|
P. graveolens | 0 | 8.94 ± 0.63 | 23.35 ± 0.91 |
50 | 0.66 ± 0.14 | 1.87 ± 0.23 | |
75 | 2.59 ± 0.51 | 8.75 ± 0.75 | |
100 | 1.06 ± 0.27 | 3.82 ± 0.34 | |
M. longifolia | 0 | 3.37 ± 0.65 | 4.47 ± 0.69 |
50 | 13.13 ± 0.86 | 28.96 ± 1.28 | |
75 | 2.32 ± 0.47 | 7. 47 ± 0.62 | |
100 | 25.81 ± 0.94 | 39.42 ± 2.17 | |
C. frutescens | 0 | 42.07 ± 1.85 | 58.76 ± 1.08 |
50 | 47.55 ± 1.96 | 62.21 ± 1.23 | |
75 | 105.23 ± 2.84 | 175.78 ± 6.52 | |
100 | 77.51 ± 2.17 | 122.91 ± 3.44 | |
Control | Doxorubicin | 2.62 ± 0.09 | 0.49 ± 0.07 |
