Table 2 Demographics, symptom durations, appendicolith statuses, serum concentrations of standard inflammatory markers and IgA of 137 children with confirmed appendicitis.

From: Serum immunoglobulin A in pediatric appendicitis

 

Uncomplicated appendicitis n = 79

Complicated appendicitis n = 58

p-value

Age (years)

11 (9–13)

9 (7–12)

0.005

Sex (male)

48 (61%)

38 (66%)

0.596

Symptom duration (h)

0.063

0–24

41 (52%)

18 (31%)

 

24–48

27 (34%)

23 (40%)

 

48–96

10 (13%)

14 (24%)

 

>96

0 (0%)

2 (3%)

 

Appendicolith present

13 (18%)

21 (38%)

0.015

Serum IgA (g/L)

1.18 (0.80–1.58)

0.92 (0.59–1.47)

0.072

Serum IgA*

0.596

Normal

53 (67%)

43 (74%)

 

High

3 (4%)

1 (2%)

 

Low

23 (29%)

14 (24%)

 

CRP (mg/L)

27 (17–52)

57 (32–121)

< 0.001

Leukocytes (x109/L)

14.3 (11.7–17.8)

16.0 (13.1–19.2)

0.046

Neutrophils (x109/L)

11.1 (9.1–14.6)

12.9 (10.3–16.0)

0.038

Neutrophil percentage (%)

80 (73–85)

83 (76–86)

0.051

  1. *Serum IgA according to age dependent reference intervals: 21 days – 2 years: 0.01–0.50 g/L, 2–10 years: 0.4–2.5 g/L, > 10 years: 0.88–4.5 g/L17.
  2. Values are presented as median (IQR) for continuous variables and absolute numbers (%) for grouping variables. Group differences were assessed using the Mann-Whitney U test and the Chi square test, respectively. CRP: c-reactive protein; IgA: immunoglobulin A.
  3. n = 78 and 57 for symptom duration.
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