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Comprehensive indicators and fine granularity refine density scaling laws in rural-urban systems
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  • Published: 25 February 2026

Comprehensive indicators and fine granularity refine density scaling laws in rural-urban systems

  • Jack Sutton1,
  • Quentin S. Hanley1,2,
  • Gerri Mortimore3,
  • Ovidiu Bagdasar1,4,
  • Haroldo V. Ribeiro5,
  • Thomas Peron6,
  • Golnaz Shahtahmassebi7 &
  • …
  • Peter Scriven3 

Scientific Reports , Article number:  (2026) Cite this article

We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Cancer
  • Diseases
  • Health care
  • Mathematics and computing

Abstract

Density scaling laws complement traditional population scaling laws by enabling the analysis of the full range of human settlements and revealing rural to urban transitions with breakpoints at consistent population densities. However, previous studies covering all areas, not just cities, have been constrained by the granularity of available rural and urban units, as well as limitations in the quantity and diversity of indicators. This study addresses these gaps by examining Middle Layer Super Output Areas (MSOAs) in England and Wales, incorporating an extensive set of 117 indicators for the year 2021, spanning age, ethnicity, educational attainment, religion, disability, economic activity, mortality, crime, property transactions, and road accidents. Results indicate that the relationship between indicator density and population density is best described by a segmented power law model with a consistent breakpoint (33 ± 5 persons per hectare) for 92 of the 117 indicators. Additionally, increasing granularity reveals further rural to urban transitions not observed at coarser spatial resolutions. Our findings also highlight the influence of population characteristics on scaling exponents, where stratifying dementia and ischaemic heart disease by older age groups (aged 70 and above) significantly affects these exponents, illustrating a protective urban effect.

Data availability

All data generated or analysed during this study are included in this published article (and its supplementary information files). This data was compiled from a range of publicly available sources as noted in the manuscript. These are provided as the Following files: S1Dataset.csv, S2Dataset.csv, S3Dataset.csv and S4Dataset.csv.

Code Availability

We have also provided a set of R-scripts as supplementary information. This has been provided as S1Code.R.

References

  1. Kühnert, C., Helbing, D. & West, G. B. Scaling laws in urban supply networks. Phys. A: Stat. Mech. Its Appl. 363, 96–103 (2006).

    Google Scholar 

  2. Bettencourt, L. M. A., Lobo, J., Helbing, D., Kühnert, C. & West, G. B. Growth, innovation, scaling, and the pace of life in cities. Proc. Natl. Acad. Sci. 104, 7301–7306 (2007).

    Google Scholar 

  3. Bettencourt, L. M. A. The origins of scaling in cities. Sci. (1979). 340, 1438–1441 (2013).

    Google Scholar 

  4. Anabalón, A., Willison, S. & Zanelli, J. General relativity from a gauged Wess-Zumino-Witten term. Phys. Rev. D. 75, 024009 (2007).

    Google Scholar 

  5. Bettencourt, L. M. A., Lobo, J., Strumsky, D. & West, G. B. Urban scaling and its deviations: revealing the structure of Wealth, innovation and crime across cities. PLoS One. 5, e13541 (2010).

    Google Scholar 

  6. Bettencourt, L. M. A. & Lobo, J. Urban scaling in Europe. J. R Soc. Interface. 13, 20160005 (2016).

    Google Scholar 

  7. Bettencourt, L. M. A., Lobo, J. & Youn, H. The hypothesis of urban scaling: formalization, implications and challenges. arXiv preprint https://doi.org/10.48550/arXiv.1301.5919 (2013).

  8. Nordbeck, S. Urban allometric growth. Geogr. Ann. Ser. B. 53, 54–67 (1971).

    Google Scholar 

  9. Antonio, F. J., de Picoli, S., Teixeira, J. J. V. & Mendes, R. dos S. Growth Patterns and Scaling Laws Governing AIDS Epidemic in Brazilian Cities. PLoS One. 9, e111015 (2014).

    Google Scholar 

  10. Bilal, U. et al. Scaling of mortality in 742 metropolitan areas of the Americas. Sci Adv 7, 7–114 (2021).

  11. Francisco Cardoso, B. H. & Gonçalves, S. Universal scaling law for human-to-human transmission diseases. Europhys. Lett. 133, 58001 (2021).

    Google Scholar 

  12. Patterson-Lomba, O. & Gomez-Lievano, A. On the scaling patterns of infectious disease incidence in cities. Epi-SCIENCE 1, 116 (2023).

  13. Ribeiro, H. V., Sunahara, A. S., Sutton, J., Perc, M. & Hanley, Q. S. City size and the spreading of COVID-19 in Brazil. PLoS One. 15, e0239699 (2020).

    Google Scholar 

  14. Ribeiro, H. V., Oehlers, M., Moreno-Monroy, A. I., Kropp, J. P. & Rybski, D. Association between population distribution and urban GDP scaling. PLoS One. 16, e0245771 (2021).

    Google Scholar 

  15. Batty, M. & Longley, P. Fractal Cities: A Geometry of Form and Function (Academic, 1994).

  16. Arcaute, E. et al. Cities and regions in Britain through hierarchical percolation. R Soc. Open. Sci 3(4), 150691.https://doi.org/10.1098/rsos.150691 (2016).

  17. Cobb, C. W. & Douglas, P. H. A theory of production. Am. Econ. Rev. 18, 139–165 (1928).

    Google Scholar 

  18. Christensen, L. R., Jorgenson, D. W. & Lau, L. J. Transcendental logarithmic production frontiers. Rev. Econ. Stat. 55, 28 (1973).

    Google Scholar 

  19. Loureiro, N. A., Neto, C. R., Sutton, J., Perc, M. & Ribeiro, H. V. Impact of inter-city interactions on disease scaling. Sci. Rep. 15, 498 (2025).

    Google Scholar 

  20. Ribeiro, H. V., Rybski, D. & Kropp, J. P. Effects of changing population or density on urban carbon dioxide emissions. Nat. Commun. 10, 3204 (2019).

    Google Scholar 

  21. Arcaute, E. et al. Constructing cities, deconstructing scaling laws. J. R Soc. Interface. 12 (102), 2015 (2015).

    Google Scholar 

  22. Leitão, J. C., Miotto, J. M., Gerlach, M. & Altmann, E. G. Is this scaling nonlinear? R Soc. Open. Sci. 3, 150649 (2016).

    Google Scholar 

  23. Altmann, E. G. Statistical Laws in Complex Systems: Combining Mechanistic Models and Data Analysis (Springer Nature Switzerland, 2024). https://doi.org/10.1007/978-3-031-73164-8

  24. Sutton, J., Shahtahmassebi, G., Hanley, Q. S. & Ribeiro, H. V. A heteroscedastic bayesian generalized logistic regression model with application to scaling problems. Chaos Solitons Fractals. 182, 114787 (2024).

    Google Scholar 

  25. Sutton, J., Shahtahmassebi, G., Ribeiro, H. V. & Hanley, Q. S. Population density and spreading of COVID-19 in England and Wales. PLoS One. 17, e0261725 (2022).

    Google Scholar 

  26. Hanley, Q. S., Lewis, D. & Ribeiro, H. V. Rural to urban population density scaling of crime and property transactions in english and Welsh parliamentary constituencies. PLoS One. 11, e0149546 (2016).

    Google Scholar 

  27. Sutton, J., Shahtahmassebi, G., Ribeiro, H. V. & Hanley, Q. S. Rural–urban scaling of age, mortality, crime and property reveals a loss of expected self-similar behaviour. Sci. Rep. 10, 16863 (2020).

    Google Scholar 

  28. Ribeiro, H. V., Hanley, Q. S. & Lewis, D. Unveiling relationships between crime and property in England and Wales via density scale-adjusted metrics and network tools. PLoS One. 13, e0192931 (2018).

    Google Scholar 

  29. Batty, M. The New Science of Cities (MIT Press, 2013).

  30. Muggeo, V. M. R. Estimating regression models with unknown break-points. Stat. Med. 22, 3055–3071 (2003).

    Google Scholar 

  31. Muggeo, V. M. R. Interval Estimation for the breakpoint in segmented regression: a smoothed score-based approach. Aust N Z. J. Stat. 59, 311–322 (2017).

    Google Scholar 

  32. Muggeo, V. M., Atkins, D. C., Gallop, R. J. & Dimidjian, S. Segmented mixed models with random changepoints: a maximum likelihood approach with application to treatment for depression study. Stat. Modelling. 14, 293–313 (2014).

    Google Scholar 

  33. Burnham, K. P. & Anderson, D. R. Model Selection and Multimodel Inference: A Practical Information-Theoretic Approach (Springer New York, 2002). https://doi.org/10.1007/b97636

  34. R Core Team. R: A Language and Environment for Statistical Computing. Preprint at https://www.r-project.org/ (2013).

  35. Dragulescu, A. A. & Arendt, C. Read, Write, Format Excel 2007 and Excel 97/2000/XP/2003. CRAN: Contributed Packages Preprint at (2018). https://cran.r-project.org/package=xlsx

  36. Chan, C., Chan, G. C. H., Leeper, T. J., Becker, J. & rio A Swiss-army knife for data file I/O. CRAN: Contributed Packages Preprint at https://rdrr.io/cran/rio/man/rio.html (2021).

  37. Muggeo, V. M. R. Testing with a nuisance parameter present only under the alternative: a score-based approach with application to segmented modelling. J. Stat. Comput. Simul. 86, 3059–3067 (2016).

    Google Scholar 

  38. Fasola, S., Muggeo, V. M. R. & Küchenhoff, H. A heuristic, iterative algorithm for change-point detection in abrupt change models. Comput. Stat. 33, 997–1015 (2018).

    Google Scholar 

  39. Warnes, G. R. et al. Gplots: various R programming tools for plotting data. CRAN: Contributed Packages Preprint at. https://doi.org/10.32614/CRAN.package.gplots (2022).

    Google Scholar 

  40. BBC News. Greater Manchester Police ‘failed to record 80,000 crimes in a year’. https://www.bbc.co.uk/news/uk-england-manchester-55251366 (2020).

  41. Neanidis, K. C. & Rana, M. P. Crime in the era of COVID-19: evidence from England. SSRN Electron. J. https://doi.org/10.2139/ssrn.3784821 (2022).

    Google Scholar 

  42. Cabrera-Arnau, C., Curiel, P., Bishop, S. R. & R. & Uncovering the behaviour of road accidents in urban areas. R Soc. Open. Sci. 7, 191739 (2020).

    Google Scholar 

  43. Finance, O. & Cottineau, C. Are the absent always wrong? Dealing with zero values in urban scaling. Environ. Plan. B Urban Anal. City Sci. 46, 1663–1677 (2019).

    Google Scholar 

  44. UK Government. What qualification levels mean. https://www.gov.uk/what-different-qualification-levels-mean/list-of-qualification-levels

  45. Devanand, D. P. et al. Computerized games versus crosswords training in mild cognitive impairment. NEJM Evidence 1, EVIDoa2200121.https://doi.org/10.1056/EVIDoa2200121(2022).

  46. OECD. Fiscal Sustainability of Health Systems: How To Finance More Resilient Health Systems when Money Is Tight? https://doi.org/10.1787/880f3195-en (OECD, 2024).

Download references

Funding

This research was funded by East Midland’s Secure Data Environment as part of the NHS England initiative. Additional support was provided by ‘1 Decembrie 1918’ University of Alba Iulia through scientific research funds. Thomas Peron acknowledges support from FAPESP (Gran No. 2023/07481-6) and CNPq/Brazil (Grant No. 310248/2023-0).

Author information

Authors and Affiliations

  1. College of Science and Engineering, University of Derby, Markeaton Street, Derby, DE22 3AW, UK

    Jack Sutton, Quentin S. Hanley & Ovidiu Bagdasar

  2. GH and Q Services Limited, West Studios, Sheffield Road, Chesterfield, S41 7LL, UK

    Quentin S. Hanley

  3. College of Health, Psychology and Social Care, University of Derby, Kedleston Road, Derby, DE22 1GB, UK

    Gerri Mortimore & Peter Scriven

  4. Department of Mathematics, Faculty of Exact Sciences, “1 Decembrie 1918” University of Alba Iulia, Alba Iulia, 510009, Romania

    Ovidiu Bagdasar

  5. Departamento de Fisica, Universidade Estadual de Maringa, Maringa, 87020- 900, PR, Brazil

    Haroldo V. Ribeiro

  6. Institute of Mathematics and Computer Science, Universidade de Sao Paulo, Avenida Trabalhador Sao Carlense, 400-Centro, Sao Carlos, 13566-590, Brazil

    Thomas Peron

  7. School of Science and Technology, Nottingham Trent University, Nottingham, NG11 8NS, United Kingdom

    Golnaz Shahtahmassebi

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Contributions

J.S., Q.S.H., G.M., O.B., H.V.R., T.P., G.S., and P.S. designed research, performed research, analysed data, and wrote the paper.

Corresponding author

Correspondence to Jack Sutton.

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Cite this article

Sutton, J., Hanley, Q.S., Mortimore, G. et al. Comprehensive indicators and fine granularity refine density scaling laws in rural-urban systems. Sci Rep (2026). https://doi.org/10.1038/s41598-026-40238-7

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  • Received: 25 March 2025

  • Accepted: 11 February 2026

  • Published: 25 February 2026

  • DOI: https://doi.org/10.1038/s41598-026-40238-7

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