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Prevalence of stroke high-risk population and its associated factors in Neijiang
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  • Published: 21 February 2026

Prevalence of stroke high-risk population and its associated factors in Neijiang

  • Xuedong Liu1,
  • Yan Wu2,
  • Liang Li2,
  • Li Zhou2,
  • Xiufang Xie3,
  • Jian Cao1 &
  • …
  • Xianhua Li1 

Scientific Reports , Article number:  (2026) Cite this article

We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Diseases
  • Health care
  • Medical research
  • Risk factors

Abstract

This study aimed to estimate the prevalence of stroke high-risk population and its associated factors among residents aged ≥ 40 years in Neijiang, Sichuan Province, China. A population-based cross-sectional study was conducted in Neijiang from May 2023 to October 2024. Simple random sampling was employed to recruit 6,072 residents aged ≥ 40 years. Data were collected through face-to-face interviews using a standardized questionnaire. Descriptive, comparative, and multivariate analyses were used for data processing. 95% confidence intervals (CIS) were calculated using the Wilson EB and Newcombe RG methods. Of the 6,072 residents, the prevalence of stroke high-risk population was 24.52% (95% CI: 23.45%-25.62%). The prevalence was significantly higher in men (32.66% vs. 20.47%, P < 0.001), rural residents (28.23% vs. 20.67%, P < 0.001), residents with lower average annual income (26.16% vs. 22.79%, P = 0.002), and those engaged in physical labor (26.76% vs. 23.72% vs. 22.48% vs. 18.25%, P < 0.001). Furthermore, the prevalence increased with age (16.23% vs. 22.91% vs. 27.08%, P < 0.001), but decreased with educational level (27.33% vs. 23.37% vs. 22.05% vs. 17.21%, P < 0.001). Residents with hypertension, dyslipidemia, diabetes mellitus, atrial fibrillation, smoking, overweight, physical inactivity, or family history of stroke had a significantly higher prevalence than those without these factors. The top three prevalent factors for stroke high-risk population were hypertension (82.20%), dyslipidemia (72.26%), and physical inactivity (42.04%). Hypertension (OR = 291.829, 95% CI = 185.207-459.831), physical inactivity (OR = 274.455, 95% CI = 170.791-441.039), and diabetes mellitus (OR = 268.155, 95% CI = 165.782-433.745) were the top three factors associated with stroke high-risk population stratification. The prevalence of stroke high-risk population is high among residents aged ≥ 40 years in Neijiang. Men, elderly, rural residents, residents with lower average annual income and educational level, and those engaged in physical labor had higher prevalence of stroke high risk. Hypertension, dyslipidemia, and physical inactivity were the top three prevalent risk factors. Furthermore, hypertension, physical inactivity, and diabetes mellitus were the top three factors associated with stroke high-risk population stratification.

Data availability

The datasets generated and/or analysed during the current study are not publicly available due to privacy concerns but are available from the corresponding author on reasonable request.

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Acknowledgements

We would like to thank the field investigators from Community Health Services Centers and Township Health Centers in Neijiang, whose diligent efforts in conducting face-to-face interviews and promptly uploading survey data were strong supports to this study. Special thanks to the Neijiang Health Commission and the Neijiang Centers for Disease Prevention and Control for their unwavering support and professional guidance throughout the implementation of this study.

Funding

This study was supported by the National Health Commission Capacity Building and Continuing Education Center (GWJJMB202510021023).

Author information

Authors and Affiliations

  1. Department of Medical Administration, The First People’s Hospital of Neijiang, No.1866, West Han’an Avenue, Shizhong District, Neijiang, 641000, PR China

    Xuedong Liu, Jian Cao & Xianhua Li

  2. Department of Neurology, The First People’s Hospital of Neijiang, No.1866, West Han’an Avenue, Shizhong District, Neijiang, 641000, PR China

    Yan Wu, Liang Li & Li Zhou

  3. Department of Respiratory Medicine, The First People’s Hospital of Neijiang, No.1866, West Han’an Avenue, Shizhong District, Neijiang, 641000, PR China

    Xiufang Xie

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Contributions

LXD: Conceptualization, Methodology, Software, Data Curation, Formal Analysis, Writing-Original Draft, Writing-Review & Editing.WY: Investigation, Data Curation, Supervision, Project Administration.LL: Conceptualization, Data Curation, Project Administration.ZL: Supervision, Project Administration.XXF: Supervision, Project Administration.CJ: Supervision, Project Administration.LXH: Project Administration, Funding acquisition.

Corresponding authors

Correspondence to Yan Wu, Jian Cao or Xianhua Li.

Ethics declarations

Ethics approval and consent to participate

This was a population-based cross-sectional study based on the 2023–2024 CNSSS data in Neijiang. This study was endorsed by the Office of the CSPPC and was conducted in accordance with the Declaration of Helsinki. Additionally, ethics approval for this study was confirmed by the Ethics Committee of the First People’s Hospital of Neijiang (2025-Ethical approval-038-01). All participants were required to sign written informed consent prior to their involvement in the study.

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The authors declare no competing interests.

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Cite this article

Liu, X., Wu, Y., Li, L. et al. Prevalence of stroke high-risk population and its associated factors in Neijiang. Sci Rep (2026). https://doi.org/10.1038/s41598-026-40275-2

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  • Received: 23 November 2025

  • Accepted: 11 February 2026

  • Published: 21 February 2026

  • DOI: https://doi.org/10.1038/s41598-026-40275-2

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Keywords

  • Stroke
  • Prevalence
  • High-risk population
  • Neijiang
  • China
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