Table 5 Results of bivariate meta-regression models: association between sampling parameters and molecular analysis methods with the positivity rate of airborne SARS-CoV-2 collected on filters

From: Systematic review and meta-analysis of methodological approaches for characterising airborne SARS-CoV-2 RNA for environmental surveillance

 

Coefficient (95% Confidence Interval)

SE*

P-value

I**,2

Environments

   

46.84%

Healthcare

Ref.

   

Socio-health

-0.08 (-0.34 0.19)

0.13

0.574

 

Transport

0.66 (-0.23 1.55)

0.44

0.144

 

Other indoor

0.28 (0.05, 0.51)

0.11

0.018

 

Air flow sampling (L/min x 10-4)

2 (-9, 13)

5

0.696

46.87%

Volume of sampling (m3 air)

0.03 (0.01, 0.04)

0.01

<0.001

28.88%

Time of sampling (min x 10-6)

4.29 (-78.4, 69.8)

36.4

0.907

57.93%

Type of filter

   

47.32%

PTFE filter

Ref.

   

Gelatine filter

0.08 (-0.08, 0.23)

0.08

0.340

 

Other type of filter

0.20 (0.02, 0.39)

0.09

0.033

 

Samples storage

   

0%

 ~ -80°C

Ref.

   

Pretreatment and -80°C

-0.05 (-0.25, 0.14)

0.09

0.591

 

4 °C

0.56 (0.16, 0.97)

0.19

0.009

 

Analysis in hours

0.23 (0.10, 0.36)

0.06

0.001

 

 ~ -20°C

0.10 (-0.16, 0.18)

0.08

0.902

 

Target gene

   

50.25%

N

Ref.

   

ORF1

0.02 (-0.21, 0.26)

0.11

0.861

 

E

0.19 (-0.05, 0.44)

0.12

0.112

 

S

0.08 (-0.36, 0.51)

0.21

0.718

 

UTR

-

-

-

 
  1. *SE Standard Error.
  2. **I2 Proportion of residual variation due to heterogeneity.