Fig. 2: Histopathological evaluation of liver, duodenum and gWAT. | Lab Animal

Fig. 2: Histopathological evaluation of liver, duodenum and gWAT.

From: A novel model of cardiovascular–kidney–metabolic syndrome combining unilateral nephrectomy and high-salt–sugar–fat diet in mice

Fig. 2

Microscopic analyses of samples from mice subjected to UNX that consumed WD rich in salt for 12 and 20 weeks, compared with the control group. Samples stained with hematoxylin–eosin (HE). Top: photomicrographs of the liver parenchyma showing normal liver architecture, absence of inflammatory infiltrate and no signs of increased deposition of fat globules (20× objective). Middle: photomicrographs of the cross-section of the duodenal wall, to measure the size of the villi and crypts and evaluate the absorption surface and intestinal morphology (10× objective). Bottom: photomicrographs of gWAT with an evident increase in the average size of adipocytes in the groups exposed to UNX + WD compared with adipocytes from the same tissue in the sham-operated control group (20× objective).

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