Extended Data Fig. 5: ISO increases the induction of regular supraventricular tachyarrhythmias in males only.

A: Comparison of regular supraventricular tachyarrhythmias (SVT) induction (%) under UAS, ISO and PEN, stratified by sex. B: Comparison between males and females. The Δ change in SVT induction (%) relative to UAS under ISO and PEN conditions. C-D: Similar representations as in A-B but for SVT duration. Statistical analysis: A, C: Friedman’s and Dunn’s multiple comparisons. B, D: Mann–Whitney test. For clarity, two data points in C and two in D were out of scale and are not represented.