Table 1 Information on NHP studies sourced for this study43,44,45,46,47, including unpublished ongoing studies

From: Biochemical and hematological reference intervals in rhesus and cynomolgus macaques and implications for vaccine and drug development

Year study performed

Species and sample size

Age range (years)

Vaccine types

Administration route

Reference

2016

Indian Macaca mulatta, n = 24 (14 M + 10 F)

M: 2.7–4.2, F: 2.7–3.7

Protein vaccine in adjuvant

s.c. or i.m.

Thompson et al.45

2017

Indian Macaca mulatta, n = 14 (4 M + 10 F)

M: 4.0–4.3, F: 3.8–4.8

Protein vaccine in adjuvant

i.m.

Ols et al.46

2018

Chinese Macaca mulatta, n = 18 (9 M + 9 F)

M: 3.2–3.5, F: 3.1–3.5

mRNA vaccine or inactivated virus vaccine

i.m.

Hellgren et al.43

2018

Chinese Macaca mulatta, n = 18 (9 M + 9 F)

M: 3.4–3.7, F: 3.3–3.8

mRNA vaccine

i.m.

Not yet published

2020–2021

Indian Macaca mulatta, n = 12 (6 M + 6 F)

M: 4.3–6.8, F: 4.4–6.3

Protein vaccine in adjuvant

i.m.

Lenart et al.44

2020–2021

Indian Macaca mulatta, n = 12 (9 M + 3 F)

M: 4.4–6.2, F: 5.1–5.2

Peptides with anti-CD40 mAb

s.c. or i.v.

Yan et al.47

2023

Indian Macaca mulatta, n = 15 (8 M + 7 F)

M: 7.4–9.3, F: 7.4–9.4

mRNA vaccine

i.m.

Not yet published

2023

Macaca fascicularis, n = 20 (10 M + 10 F)

M: 4.2–4.5, F: 3.9–6.4

Protein vaccine in adjuvant

i.m.

Not yet published

2023

Macaca fascicularis, n = 2 (2 F)

F: 11.5–16.8

Peptides with anti-CD40 mAb

s.c.

Not yet published

  1. i.m., intramuscular injection; i.v., intravascular injection; mAb, monoclonal antibody; s.c., subcutaneous injection.