Fig. 4 | npj Precision Oncology

Fig. 4

From: Superhydrophobic lab-on-chip measures secretome protonation state and provides a personalized risk assessment of sporadic tumour

Fig. 4

Data set of the secretome made by cultures of non-haematological cells isolated by liquid biopsy of control and cancer patients measured through the device was subjected to ANOVA analysis. Graphical ANOVA from Bonferroni post hoc test shows control C dissimilar from patients P samples with a 95% confidence interval and 5% significance level, for both time constant (a, b) modulation (c, d) measured variables. Interaction plots carried out on time constant (b) modulation (d) outputs, showing significant discrimination between C and P samples for values of potential at the gate V higher than V3. PCA analysis performed to reduce noise and extract from the whole data set combinations of voltage and sensor number, V–S, in correspondence of which sample separation may be optimized (e)

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