Fig. 3: Expression profile of TIME factors across multiple cancer types. | npj Precision Oncology

Fig. 3: Expression profile of TIME factors across multiple cancer types.

From: Genomic investigation of co-targeting tumor immune microenvironment and immune checkpoints in pan-cancer immunotherapy

Fig. 3

a Expression profile of MET in multiple cancer types. GEPIA generated dot plots profiling the tissue-wise expression patterns of MET across multiple cancer types (TCGA tumor) and paired normal tissue samples (TCGA normal + GTEx normal). Each dot represents the individual expression of a distinct tumor or normal sample. b Summary of expression profiles of TIME factors in multiple cancer types. Differential expression profiles of TIME factors were individually analyzed using GEPIA and subsequently integrated together. Red blocks represent the TIME factors upregulated in the tumor, green blocks represent the TIME factors downregulated in the tumor, and blank blocks indicate the ones are not significantly differentially expressed between tumoral and normal tissues. The ANOVA method was used for differential gene expression analysis, and genes with higher |log2FC| values (> 1) and lower q values (< 0.01) were considered differentially expressed genes.

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