Fig. 3: Circulating tumor fraction estimate (ctFE) and mutational landscape by cancer type.
From: Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNA
a Median ctFE among the most common cancer types was 0.07, with the exception of prostate (ctFE = 0.06). b The mutational landscape was evaluated in the xF 1000 cohort, with variants categorized as reportable, pathogenic, or actionable. Across all patients, the most commonly mutated gene was TP53. The heatmap was normalized within rows to depict the most prevalent variants detected for each common cancer type in the cohort (breast n = 254, colorectal n = 98, lung n = 241, prostate n = 96, and pancreatic n = 83).
