Table 3 Tumor’s characteristics.
Biopsy | Case 1 | Case 2 | Case 3 | |||
|---|---|---|---|---|---|---|
Pre | Post | Pre | Post | Pre | Post | |
ER | Neg | 5% | Neg | Neg | Neg | Neg |
PR | Neg | Neg | Neg | Neg | Neg | Neg |
HER2 | Neg | Neg | Neg | Neg | Neg | Neg |
AR | 100% | 100% | Neg | Neg | Neg | Neg |
Ki67 | 50% | 30% | 50% | 80% | 60–80% | 50% |
PD-L1 | 1–10% | 10–20% | n/a | Neg | Neg | n/a |
CNA (Copies) | CCND1 (84), FGF3 (44) | CCND1 (51), FGF3 (45) | ND | ND | MYC (8.5), RB1 (0.96) | n/a |
SNV (%VAF) | TP53 (63%), FGFR4 (64%) | TP53 (86%), FGFR4 (65%) | RB1, TP53, ALK, MDC1 | RB1, TP53, ALK, MDC1 | TP53 (70%) | n/a |
MSI | Stable | Stable | Stable | Stable | Stable | n/a |
