Table 1 Summary table of calculated IC50 values for parental and trametinib-resistant cell lines.

From: MEK inhibitor resistance in lung adenocarcinoma is associated with addiction to sustained ERK suppression

Cell line

Parental IC50 nM

TramR IC50 μM

H1792 sgControl

20.3 (14.4–28.5)

>10

H1792 sgRB1#7

22.4 (16.4–30.4)

>10

H1792 sgRB1#14

37.6 (28.6–49.4)

>10

H358 sgControl

3.7 (2.7–5.1)

>10

H358 sgRB1#3

5.9 (3.9–8.9)

>10

H358 sgRB1#4

6.8 (5.1–9.1)

>10

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