Fig. 3: The impact of AID mutations on ICI response. | npj Precision Oncology

Fig. 3: The impact of AID mutations on ICI response.

From: Pan-cancer landscape of AID-related mutations, composite mutations, and their potential role in the ICI response

Fig. 3

Meta-analysis of the survival impact of the fraction of AID mutations in different studies. a Effect of using AID/APOBEC (5th decile as cutoff) or SNV substitutions where AID remains significant across all the studies. b Forest plot of a Cox model of the global impact, after adjustment by TMB (top 20%), median APOBEC mutations, age, and gender. c Forest plot of the Cox model of the impact of AID mutations per cancer subtype.

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