Fig. 4: Performance of the MSI-H predictor on Gleason score and procedure type subgroups.

Receiver operating characteristic (ROC) curves (a, b) and violin plots (c, d) of prediction scores for Gleason score (a, c) and procedure type (b, d) clinical subgroups in the pooled validation set that combines the internal scans of the paired validation set and the temporal validation set. The shared areas represent the 95% confidence intervals of the ROC curves. P-value annotation legend: ns: p ≤ 1, *: 0.01 < p ≤ 0.05, **: 0.001 < p ≤ 0.01, ***: 0.0001 < p ≤ 0.001, ****: p ≤ 0.0001.