Table 2 Distribution of mismatch repair (MMR) immunohistochemical (IHC) stain findings for prostate cancer cases

From: Development and validation of a deep learning-based microsatellite instability predictor from prostate cancer whole-slide images

IHC staining pattern

Number of MSI-H samples

Number of MSS samples

MSH2/MSH6 Loss

32

6

MLH1/PMS2 Loss

4

0

MSH6 loss only

0

3

PMS2 loss only

1

2

All present

1a

1345

MMR IHCs not available

100

4044

  1. aFor the one MSI-H case where all MMR staining patterns were present, NGS detected an MSH6 missense mutation (E1193K).