Fig. 2: DNA methylation and gene expression pattern.
From: Molecular landscape and multi-omic measurements of heterogeneity in fetal adenocarcinoma of the lung
a, b t-distributed stochastic neighbor embedding (t-SNE) plot showing the extent of epigenomic (a) and transcriptomic (b) variation within and across tumor and non-malignant tissue regions from the patients. Non-malignant tissues from different patients are shown in hollow circles, whereas tumor tissues from different patients are shown in filled circles. H-FLAC and L-FLAC samples are shown in different colors. c Pathway enrichment comparison between H-FLAC and L-FLAC based on differentially methylation region (DMR) results. d Pathway enrichment comparison between H-FLAC and L-FLAC based on differentially expressed gene (DEG) results.
