Fig. 2: Classification of EC subtypes. | npj Precision Oncology

Fig. 2: Classification of EC subtypes.

From: Single-cell and spatial transcriptomics reveals the key role of MCAM+ tip-like endothelial cells in osteosarcoma metastasis

Fig. 2

A ECs were categorized into seven distinct subtypes. B The marker genes of each EC subtype. C Gene expression heatmap in EC subtypes. D Composition of EC subtypes among different groups. E GSVA analysis showed that the tip-like ECs subtype was significantly enriched in the NOTCH SIGNALING pathway, WNT BETA CATENIN SIGNALING, and APICAL JUNCTION pathway etc. F Lung metastasis scores were the highest in tip-like ECs by AUCell. G Angiogenesis scores were the highest in tip-like ECs by AUCell.(Proli: proliferative).

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