Fig. 3: Cellular communication and differential gene analysis between osteosarcoma groups. | npj Precision Oncology

Fig. 3: Cellular communication and differential gene analysis between osteosarcoma groups.

From: Single-cell and spatial transcriptomics reveals the key role of MCAM+ tip-like endothelial cells in osteosarcoma metastasis

Fig. 3

A Heatmap of cellular interactions between tip-like ECs and other clusters. B Cellular ligand-receptor bubble maps of osteoblasts and tip-like ECs. C Differential gene volcano plots of tip-like ECs in the PT group versus the PC group. D GSEA plot of differentially expressed genes in tip-like ECs in PT versus the PC group. E Differential gene volcano plot of tip-like ECs in Met-Lung group versus the PC group. F GSEA plot of differentially expressed genes in tip-like ECs in Met_Lung versus the PC group (PT primary tumor, PC paracancerous, Met-Lung lung metastasis).

Back to article page