Table 1 Overview of the tools benchmarked in this study

From: Benchmarking mouse contamination removing protocols in patient-derived xenografts genomic profiling

Protocols

Input

Aligner

Output

Algorithm

Language

Release

Disambiguate

BAM, name sorted

STAR, HISAT, BWA

BAM

Mapping score and quality

Python, C + +

2016

Bamcmp

BAM, name sorted

STAR, HISAT, BWA

BAM

Mapping score and quality

C + +

2017

XenofilteR

BAM, coordinate sorted

STAR, HISAT, BWA

BAM

Mapping score and quality

R

2018

Xenome

Fastq

NA

Fastq

K-mer

C + +

2012

BBSplit

Fastq

BBMAP

Fastq

K-mer

Java

2020

Xengsort

Fastq

NA

Fastq

K-mer

Python, numba

2021