Table 4 Performance on RX dataset

From: Establishing predictive machine learning models for drug responses in patient derived cell culture

Rspearman

Library (viability)

Top 5 ranked (viability)

n hits available

n hits predicted

n hits identified

n drugs available

0.62/0.02

87.55

33.45/2.83

4.36

4.87/0.27

3.60/0.11

33.00

  1. For the 24 cell lines, the mean Spearman rank is given for the entire library of 30+ drugs. The average viability resulting from the entire drug library is reported, along with that found when selecting the top 5 predicted drugs. Defined as reducing cell viability to less than thirty percent, the average number of hits available per cell line is shown, as well as the average number of drugs predicted to be hits, and the average number of these correctly identified as such. The average number of drugs tested per cell line is found in the last column ‘n drugs available’. The results from five independent experiments are shown as mean/standard deviation.
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