Fig. 3: Myeloid lineage differentiation in the TME of NF1 tumors. | npj Precision Oncology

Fig. 3: Myeloid lineage differentiation in the TME of NF1 tumors.

From: Natural history of SPP1 signaling in NF1 tumors

Fig. 3

A Subclustering of myeloid lineage in pNFs. B Pseudotime analysis of myeloid lineage differentiation in pNFs. C SPP1 expression in pNF myeloid cells along the pseudotime. D S100A8, IL1B, and C1QC expression along the pseudotime. E Subclustering of myeloid lineage in MPNSTs. F Pseudotime analysis of myeloid lineage differentiation in MPNSTs. G SPP1 expression in MPNST myeloid cells along the pseudotime. H S100A8, IL1B, and C1QC expression along the pseudotime in MPNSTs. pDC plasmacytoid dendritic cells; moDC monocyte-derived dendritic cells; cDC1 conventional dendritic cells type 1.

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