Fig. 2: Prognosis evaluation and pseudotime trajectory analysis of neutrophil subclusters in PDAC. | npj Precision Oncology

Fig. 2: Prognosis evaluation and pseudotime trajectory analysis of neutrophil subclusters in PDAC.

From: Single-cell transcriptome analysis identifies MIF as a novel tumor-associated neutrophil marker for pancreatic ductal adenocarcinoma

Fig. 2

A–G Kaplan‒Meier survival curves illustrating the overall survival of 141 PDAC patients in the TCGA-PAAD cohort. The patients were equally divided into two groups on the basis of the score of the neutrophil subcluster signature. The score was assessed by GSVA. H Pseudotime trajectory analysis showing the differentiation of neutrophils. Left: Each point was a cell and was assigned a color on the basis of its subcluster. Right: Each point was a cell and was assigned a color on the basis of its pseudotime value. I, J Plots displaying the pseudotime-ordered expression and transcript accumulation of selected genes. *p < 0.05; **p < 0.01; ***p < 0.001.

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