Fig. 3: The functions of neutrophil subclusters in PDAC. | npj Precision Oncology

Fig. 3: The functions of neutrophil subclusters in PDAC.

From: Single-cell transcriptome analysis identifies MIF as a novel tumor-associated neutrophil marker for pancreatic ductal adenocarcinoma

Fig. 3

A Box plots showing the scores for hypoxia, neutrophil extracellular trap (NET) and ferroptosis in each neutrophil subcluster. B Heatmap illustrating the differences in 50 hallmark pathways of each neutrophil subcluster according to GSVA. C Scatter plot showing the differentially expressed genes (DEGs) between Neu_07_MIF and Neu_06_OLR1. The x-axis represents the difference in the percentage of cells expressing DEGs. The selection criteria for DEGs were as follows: abs(log2FC) > 1 and adjusted p < 0.05. D Bar plot showing the differences in 50 hallmark pathways between Neu_07_MIF and Neu_06_OLR1 through GSEA. E Scatter plot showing the DEGs between Neu_05_IFIT1 and Neu_04_STAT1. The selection criteria for differential genes were as follows: abs(log2FC) > 0.5 and adjusted p < 0.05. F Bar plot depicting the differences in 50 hallmark pathways between Neu_05_IFITM1 and Neu_04_STAT1 through GSEA.

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