Fig. 3: APOE-high myeloid cells exhibit a pro-tumoral phenotype in metastatic LNs.

A Volcano plot illustrating differential gene expression in APOE-high myeloid cells between metastatic LN and control LN groups. B Enriched APOE-high myeloid cell pathways in the metastatic LN group as compared to controls. C Dot plot categorized by functional groups in APOE-high myeloid cells showing the differential expression of select genes between control and metastatic LN groups. D Violin plot demonstrating percentages of CD206 + CD64+ myeloid cells between control and metastatic LN groups from the CyTOF data. Statistical significance was determined by Mann–Whitney test (*p < 0.05).