Fig. 6: Validation of APOE-high myeloid cell enrichment in metastatic LNs using an independent cohort. | npj Precision Oncology

Fig. 6: Validation of APOE-high myeloid cell enrichment in metastatic LNs using an independent cohort.

From: APOE-high myeloid cells are uniquely associated with metastatic intrathoracic lymph nodes obtained by EBUS-TBNA in primary lung cancer

Fig. 6

A Dot plot showing the expression of canonical marker genes for immune cell types. B Stacked bar plots showing the percentage and Chi-squared test result of each cell type in the control and metastatic LN groups. Cell types are color-coded as indicated in the legend. C Enriched pathways in the metastatic LN group compared to control LN group in CD8 T cells. D Dot plot showing the differential expression of select DEGs categorized by functional groups in CD8 T cells from the control and metastatic LN groups. E Enriched pathways in the metastatic LN group compared to control LN group in APOE-high myeloid cells. F Dot plot showing the differential expression of select DEGs categorized by functional groups in APOE-high myeloid cells from the control and metastatic LN groups.

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