Fig. 6: Heterogeneity of spatially resolved breast cancer intrinsic subtypes in the TNBC tumor. | npj Precision Oncology

Fig. 6: Heterogeneity of spatially resolved breast cancer intrinsic subtypes in the TNBC tumor.

From: Computational pathology annotation enhances the resolution and interpretation of breast cancer spatial transcriptomics data

Fig. 6

a Spatially resolved intrinsic subtypes predicted by the AIMS method across all four sections of BCSA1. The folded area in TumA2 was excluded from the analysis. The scarlet color code indicates Basal-Like (BL), fuchsia pink represents HER2, and green denotes Normal Breast-Like (NBL). Scale bar 1 mm. b Pie chart showing the overall distribution of predicted intrinsic subtypes from all BCSA1 sections. c Stacked columns displaying the composition of GEX clusters within the BL, HER2, and NBL subtypes. d Percentage of immune, stroma, and tumor cells in each intrinsic subtype predicted by CTA. Immune in yellow, stroma in blue, and tumor in pink.

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