Table 1 List of sensors and their respective domains and metrics
From: Digital biomarkers for Alzheimer’s disease: the mobile/wearable devices opportunity
Sensor | Metrics | Sense—Domain | Reference |
|---|---|---|---|
Camera | Saccades, saccades in reading | Occulomotor—eye movements | |
Novelty preference | Occulomotor—eye movements | ||
Constriction reflex in response to stimuli | Occulomotor—pupillary response | ||
Multiple face features | Behavior—facial expressions | ||
Microphone | Voice power spectrum and tremor | Speech and language—voice features | |
Vocabulary, syntactic and semantic qualities, pauses, others | Speech and language—cognition | ||
Ambient noise level—dominant frequencies | Environment | ||
Accel/gyro | Gait metrics, distance, steps, symmetry, etc | Movement—gross motor | |
Other activity metrics (bike, swim, run, etc) | |||
Overall activity level—energy consumption | |||
Tremor | Movement—fine motor | ||
Barometer | Gait/climb information | Movement—gross motor | |
Barometric pressure | Environment | ||
Touchscreen | Swipe pattern efficiency | Movement—fine motor | |
Keyboard typing/tapping speed | |||
Vocabulary, syntactic, and semantic qualities | Speech and Language—written text | ||
Geoposition | Location patterns | Behavior and movement—mobility and patial memory | |
Driving patterns and navigational efficiency | Executive function—reaction time and spatial memory | ||
Activity level | Movement—actigraphy | ||
Device use | PIN and password attempts, reminders use, and more | Executive function—memory | |
Number of apps used, frequency, use patterns | Executive function | ||
Behavioral disruptions, social circle size, frequency of interactions | Behavior—social interactions | ||
ECG | Heart rate (HR) and heart rate variability (HRV) | ANS function—heart electric activity | |
System recovery metrics | |||
Sleep patterns, phases and efficiency | |||
Electrical activity metrics | |||
PPG | Heart rate (HR) and heart rate variability (HRV) | ANS function—systemic circulation | |
System recovery metrics | |||
Sleep patterns, phases and efficiency | |||
Oxygen saturation (SpO2) | |||
IR thermometer | Skin temperature | Metabolic activity and hormonal Cycle | |
Immune system health, Acute illness | |||
Ballistocardiography* | Sleep patterns, sleep phases and efficiency | Sleep | |
Galvanic skin response | Skin electrical resistance | Behavior—emotional stress levels | |
ANS function—physical stress levels | |||
Ambient light sensor | Light intensity at visible wavelength | ANS function—circadian rhythm | |
Environment | |||
UV sensor | Light intensity at UV wavelength | Environment | |
Electromyogram (EMG) | Activity level | Movement—gross and fine motor | |
Tremor | ANS—neuromuscular system health | ||
Seizures |