Table 5 Additional imaging response detection performance metrics (Matthews correlation coefficients) for each model and the two types of classifier

From: High-dimensional detection of imaging response to treatment in multiple sclerosis

Predictor set

Support vector machines

Extremely randomised trees

Brain volume

0.132 [0.115–0.148]

0.179 [0.164–0.194]

Number of lesions

0.168 [0.152–0.184]

0.229 [0.214–0.243]

Total lesion volume

0.229 [0.213–0.245]

0.239 [0.223–0.255]

Best low-dimensional

0.354 [0.339–0.369]

0.355 [0.341–0.369]

Regional atrophy

0.576 [0.563–0.590]

0.620 [0.607–0.633]

Regional disconnection

0.544 [0.530–0.559]

0.559 [0.545–0.573]

Best high-dimensional

0.666 [0.653–0.679]

0.675 [0.662–0.689]

  1. All figures are given as the mean Matthews correlation coefficient [95% CI]