Fig. 1: The translational crisis in medicine.
Common log scale plot of the annual number of drugs approved by the FDA per billion US$ spending adjusted for inflation (in red, left y axis) and the annual number of articles indexed on PubMed (in black, right y axis) over the interval 1950–20101 and 20132. Note logarithmic decline of the former despite an equal and opposite rise of the latter, consistently over more than half a century.
