Table 1 Characteristics of the development and test datasets.

	Development dataset	Test dataset
Radiographs
No. of hospitals^a	15	15
No. of radiographs	715,343	16,019
No. of radiographic views	16^b	9^c
No. of anatomical regions	16	16
Median (range) radiographs per anatomical region	40,658 (6249–106,705)	1000 (774–1079)
No. of radiographs with fracture(s) (%)	82,830 (12%)	2415 (15%)
No. of fracture bounding-box annotations	97,559	2718^d
No. of bounding-box annotations per fractured radiograph, mean (range)	1.2 (1–13)	1.1 (1–6)
Patients
No. of patients	314,866	12,746
Median (range) patients per anatomical region	18,952 (3022–71,484)	909 (326–1042)
No. of male (%)	137,929^e (44%)	5520 (43%)
Median (range) patient age in years	54 (0–90)^f	55 (22–90)
Annotators
No. of orthopedic surgeons (median years experience post-residency)	18 (16)	11 (13)
No. of radiologists (median years experience post-residency)	11 (13)	7 (13)

No radiographs used for testing were in the development dataset.
^aDatasets sampled from the MedStar Health System located in Baltimore, MD, Washington, D.C., Olney, MD, Leonardtown, MD, and Clinton, MD, the CarePoint Health System in Bayonne, NJ, Jersey City, NJ, and Hoboken, NJ as well as the Hospital for Special Surgery (HSS) in New York, NY and Orthopedic Institute for Children in CA.
^bNumber of unique radiographic views estimated through a manual review of 20,000 randomly sampled radiographs across anatomical regions.
^cViews were collapsed for statistical analyses into frontal view (frontal; frontal dorso-plantar; frontal inlet-outlet), lateral view (axillary; frog-leg lateral; lateral; y), and oblique view (oblique; oblique-mortise).
^d2718 reflects unique fracture sites after fusing the 3 reference standard annotations per image through a pixel-wise majority vote.
^e602 patients were missing biological sex information.
^fPatient age missing for 43% of the development dataset because patient age was removed from radiographs collected at HSS. De-identification procedures capped patient age at 90 years. In the development dataset, 0.1% of radiographs were from patients 0 to 10 years of age, and 2.95% were from patients 10 to 20 years of age. By design, no radiographs in the test dataset were from patients <22 years of age.

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