Table 3 Accuracy and recall (sensitivity) for cancer subtype identification (vertical search) among frozen section slides.

From: Pan-cancer diagnostic consensus through searching archival histopathology images using artificial intelligence

Tumor type

WSI count

Patient count

Majority-5

Majority-10

Majority-20

   

Accuracy

Recall

Accuracy

Recall

Accuracy

Recall

Brain

        

GBM

1102

582

94.19

94.19

92.74

94.37

92.92

93.65

LGG

695

501

82.58

82.59

80.28

83.02

81.00

83.31

Endocrine

        

ACC

81

81

45.67

46.91

28.39

48.15

20.98

35.80

PCPG

174

170

85.63

86.78

86.20

89.66

83.90

86.78

THCA

514

478

97.08

97.67

97.47

98.44

97.85

98.83

Gastrointestinal tract

        

COAD

830

449

63.73

69.40

56.62

74.10

60.00

78.43

ESCA

166

165

25.90

31.33

12.04

23.49

09.03

15.66

STAD

623

428

71.10

74.48

65.48

80.42

67.41

81.70

READ

328

170

14.32

19.21

05.48

14.63

02.13

8.54

Gynecological

        

OV

1184

586

99.07

99.24

98.98

99.16

98.81

99.16

CESC

298

291

64.42

68.12

59.06

65.44

58.05

63.42

UCS

49

49

10.20

12.24

04.08

12.24

02.04

2.04

UCEC

685

524

90.07

90.80

89.05

90.80

89.34

91.68

Hematopoietic

        

DLBC

57

45

91.22

91.23

80.70

87.72

73.68

78.95

THYM

124

124

97.58

97.58

95.16

97.58

95.16

95.97

Liver, pancreaticobiliary

        

LIHC

392

370

93.36

93.88

92.60

94.64

93.62

94.90

CHOL

51

51

35.29

45.10

19.60

47.06

13.72

27.45

PAAD

216

181

91.66

91.67

90.74

93.52

90.74

93.98

Melanocytic malignancies

        

SKCM

463

460

98.70

98.49

98.48

98.92

99.56

99.78

UVM

69

69

46.37

46.38

31.88

39.13

18.84

27.54

Prostate/testis

        

TGCT

155

149

86.45

87.74

83.87

85.81

81.29

85.81

PRAD

600

485

98.33

98.33

98.33

98.33

98.50

98.67

Pulmonary

        

LUSC

745

485

78.25

78.79

70.87

77.99

73.42

77.72

LUAD

806

500

68.23

69.11

64.14

71.34

66.12

70.84

MESO

83

83

27.71

32.53

14.45

26.51

03.61

21.69

Urinary tract

        

BLCA

420

401

92.85

94.29

90.95

94.29

90.95

95.00

KICH

138

88

78.26

81.16

68.11

77.54

57.24

73.19

KIRC

1055

529

97.81

97.91

97.25

98.20

97.63

98.20

KIRP

367

282

62.12

67.30

51.22

63.76

47.13

58.86

  1. Only those primary sites were considered for vertical search which had at least two subtypes in the repository. A positive correlation of 0.57 was measured between the number of patients and the highest accuracy.