Table 4 Accuracy and recall (sensitivity) for cancer subtype identification (vertical search) among permanent diagnostic slides.

From: Pan-cancer diagnostic consensus through searching archival histopathology images using artificial intelligence

Tumor type

WSI count

Patient count

Majority-5

Majority-10

Majority-20

   

Accuracy

Recall

Accuracy

Recall

Accuracy

Recall

Brain

        

GBM

851

381

91.18

91.30

87.89

90.01

88.13

89.42

LGG

841

489

89.77

89.54

88.58

90.61

89.17

91.20

Endocrine

        

ACC

227

56

93.83

93.39

94.27

94.71

94.71

96.92

PCPG

196

176

88.77

88.78

85.71

90.31

84.18

89.29

THCA

513

500

97.66

97.86

96.68

96.89

96.49

96.70

Gastrointestinal tract

        

COAD

436

428

76.14

82.00

69.72

86.00

74.31

90.00

ESCA

157

155

59.87

69.43

45.22

64.33

39.49

55.41

READ

157

156

10.19

12.20

00.63

3.66

00.00

0.61

STAD

394

369

75.12

79.19

67.76

81.73

67.00

83.25

Gynecological

        

UCEC

566

505

92.22

93.95

91.69

95.29

92.75

95.97

CESC

277

267

62.45

64.08

54.51

64.79

49.09

58.80

UCS

90

56

42.22

51.11

32.22

48.89

27.77

40.00

OV

106

105

66.98

67.92

59.43

67.92

51.88

62.26

Hematopoietic

        

DLBC

43

43

58.13

53.49

37.20

58.14

16.27

27.91

THYM

178

120

98.87

98.88

99.43

99.44

100.00

100.00

Liver, pancreaticobiliary

        

CHOL

39

39

43.58

43.59

25.64

35.90

02.56

17.95

LIHC

378

364

93.65

94.21

93.65

94.74

94.44

95.00

PAAD

201

182

91.04

93.53

92.03

95.02

93.03

99.00

Melanocytic malignancies

        

UVM

80

80

83.75

83.75

77.50

82.50

68.75

72.50

SKCM

471

429

99.57

99.58

99.57

99.79

99.57

99.79

Prostate/testis

        

TGCT

254

149

99.21

99.61

96.85

98.82

96.06

96.06

PRAD

447

401

98.43

98.21

98.21

98.66

98.43

98.43

Pulmonary

        

LUAD

520

465

70.96

71.35

63.26

72.31

64.42

72.50

MESO

86

74

08.13

12.79

02.32

8.14

00.00

1.16

LUSC

503

472

81.70

82.31

78.13

84.10

83.30

88.47

Urinary tract

        

BLCA

454

384

95.81

96.93

94.27

95.83

93.61

95.83

KIRC

516

511

91.66

93.02

90.11

92.44

89.53

92.64

KICH

108

108

75.92

82.41

66.66

74.07

59.25

70.37

KIRP

296

272

67.22

72.64

53.04

67.91

48.31

64.86

  1. Only those primary sites were considered for vertical search which had at least two subtypes in the repository. A positive correlation of 0.49 was measured between the number of patients and the highest accuracy.