Table 5 Effect of image-related factors specifically fundus fields of view.

From: Technical and imaging factors influencing performance of deep learning systems for diabetic retinopathy

   

Fundus fields of view

   

7-field (ETDRS standard)

2-field (Optic disc and macula-centered)

1-field (Macula-centered)

SiDRP

Value (95% CI)

AUC

 

0.936 (0.927–0.944)

0.908 (0.894–0.920)

P value for AUC comparison

 

Reference

<0.001

Sensitivity

 

90.5% (87.3–93.1%)

89.4% (86.0–92.2%)

Specificity

 

91.9% (91.6–92.2%)

89.4% (89.0%–89.7%)

AFEDS

Value (95% CI)

AUC

0.949 (0.923–0.968)

0.911 (0.877–0.937)

0.895 (0.852–0.931)

P value for AUC comparison

Reference

<0.001

<0.001

Sensitivity

90.0% (81.9–95.3%)

82.6% (72.9–89.9%)

78.4% (67.3–87.1%)

Specificity

86.5% (84.6–88.3%)

84.4% (82.3–86.3%)

86.1% (84.0–88.0%)

  1. P value was calculated by bootstrap method.
  2. Datasets used for evaluation of different fundus field of views were Singapore integrated Diabetic Retinopathy Programme (SiDRP) 2014 to 2015 to evaluate 2-field and 1-field, and African American Eye Disease Study to evaluate 7-field ETDRS standard retinal images in addition to 2-field and 1-field.
  3. AUC area under receiver operating curve, CI confidence interval, ETDRS Early Treatment Diabetic Retinopathy Study, SiDRP Singapore’s national integrated Diabetic Retinopathy Screening Program, AFEDS African American Eye Disease Study.
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