Table 1 Description of the characteristics of the patient cohort included in the training and test sets and the mean and interquartile range statistics of the raw vital signs and laboratory test results used for COVID-GBM.

From: An artificial intelligence system for predicting the deterioration of COVID-19 patients in the emergency department

Characteristic

Training set

Test set

Patients, n

2943

718

 Admissions, n

3175

764

 Sex (females), n (%)

1206 (41.0)

305 (42.5)

 Age (years)*, mean (SD)

61.9 (17.6)

64.7 (17.4)

 BMI (kg/m2), mean (SD)

29.6 (6.7)

29.4 (7.3)

 Weight (kg), mean (SD)

83.1 (22.2)

82.2 (23.1)

 Survived

2405

559

Adverse events, n

1311

369

 Intubation, n (%)

386 (29.4)

97 (26.3)

 ICU admission, n (%)

387 (29.5)

113 (30.6)

 Mortality, n (%)

538 (41.0)

159 (43.1)

Chest X-ray exams, n

5224

770

 Composite outcome within 24 h, n (%)

349 (6.7)

74 (9.6)

 Composite outcome within 48 h, n (%)

553 (10.6)

101 (13.1)

 Composite outcome within 72 h, n (%)

735 (14.1)

130 (16.9)

 Composite outcome within 96 h, n (%)

876 (16.8)

156 (20.3)

 Total number of images, n

5617

832

Vital signs feature sets, n units

10,640

2776

 Heart rate, beats per minute

93.7 (25.0)

93.5 (27.0)

 Respiratory rate*, breaths per minute

22.4 (7.0)

23.4 (7.0)

 Temperature, F

99.4 (1.9)

99.4 (1.9)

 Systolic blood pressure, mmHg

130.7 (30.0)

129.8 (29.3)

 Diastolic blood pressure, mmHg

75.9 (17.0)

76.0 (18.0)

 Oxygen saturation*, %

94.1 (4.0)

93.8 (5.0)

 Provision of supplemental oxygen*, n (%)

3970 (37.3)

1166 (42.0)

Raw laboratory test results, units

  

 Albumin, g/dL

3.5 (0.9)

3.5 (0.9)

 Alanine transaminase, U/L

49.8 (32.0)

52.2 (36.0)

 Aspartate aminotransferase, U/L

67.3 (37.0)

69.7 (43.0)

 Total bilirubin, mg/dL

0.7 (0.4)

0.7 (0.4)

 Blood urea nitrogen, mg/dL

25.9 (17.0)

26.4 (18.0)

 Calcium, mg/dL

8.7 (0.8)

8.7 (0.8)

 Chloride, mEq/L

101.1 (7.0)

101.6 (7.0)

 Creatinine, mg/dL

1.6 (0.7)

1.6 (0.7)

 D-dimer, ng/mL

1321.6 (535.5)

1146.3 (618.5)

 Eosinophils, %

0.4 (0.0)

0.4 (0.0)

 Eosinophils, n

0.03 (0.00)

0.03 (0.00)

 Hematocrit, %

38.9 (7.3)

38.9 (7.5)

 Lactate dehydrogenase, U/L

412.8 (207.0)

404.0 (213.0)

 Lymphocytes, %

14.1 (10.0)

14.9 (11.0)

 Lymphocytes, n

1.0 (0.7)

1.0 (0.7)

 Platelet volume, fL

10.6 (1.4)

10.6 (1.4)

 Neutrophils, n

6.4 (4.0)

6.3 (3.8)

 Neutrophils, %

76.6 (14.0)

75.9 (13.0)

 Platelet, n

226.1 (114.0)

223.7 (103.0)

 Potassium, mmol/L

4.2 (0.8)

4.2 (0.8)

 Procalcitonin, ng/mL

1.9 (0.3)

1.9 (0.4)

 Total protein, g/dL

7.1 (1.1)

7.2 (1.0)

 Sodium, mmol/L

136.2 (6.0)

136.6 (7.0)

 Troponin, ng/mL

0.2 (0.1)

0.2 (0.1)

  1. Note that n represents a counting unit. The asterisk (*) denotes statistically significant difference with p < 0.01 between the training and test sets. We used the two-sided t-test to compare continuous variables (age, BMI, weight, vital signs, and laboratory tests) and a 2-sample z-test to compare the proportions of categorical variables (sex and provision of supplemental oxygen).