Fig. 3: Cumulative risk of disease stratified by guideline-adherent physical activity.
From: Wearable accelerometer-derived physical activity and incident disease

Depicted is the 5-year cumulative risk of heart failure, type 2 diabetes, cholelithasis, and chronic bronchitis, stratified guideline-adherent activity according to accelerometer-measured moderate-to-vigorous physical activity (MVPA, top panels) and self-reported MVPA (bottom panels). In each plot, individuals are grouped into binary categories according to the guideline-based threshold of ≥150 min of MVPA/week. Red, pink, blue, and purple strata represent individuals meeting guideline-based levels, and the teal stratum represents individuals not meeting guideline-based levels1,10,11. In each plot, the number remaining at risk over time is depicted below. Representative diseases were selected from the four categories having the greatest enrichment for associations with activity, where each disease was significantly associated with both accelerometer-measured and self-reported activity at a false discovery rate of 1%.