Fig. 1: Current development of different types of neuroimaging CAD models.
From: Challenges of implementing computer-aided diagnostic models for neuroimages in a clinical setting
Neuroimaging CAD models and analysis methods exist on a continuum of development and clinical applicability. Models that use diagnostic segmentation can be applied to brain disorders characterized by focal structural anomalies, and they are in a better position today to be applied clinically. CAD models that output a label directly can help in diagnosing neurodegenerative disorders, which have an explicit, though diffuse, structural basis, and thus CAD models can be used to detect and inform their diagnosis. However, they have yet to see widespread clinical use or a specific clinical need. Brain disorders characterized by both diffuse structural and functional qualities have been analyzed by CAD models, but specific biomarkers are elusive and their clinical implementation would require further development.
