Fig. 9: Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram of the article screening and identification process.

The initial search yielded 795 articles after applying language and publication year filters. Exclusion criteria were set to omit articles types irrelevant to our research aims, resulting in 688 potentially relevant articles. To ascertain focus on LLMs in healthcare, articles underwent a two-stage screening process. The first stage involved title and abstract screening to identify articles explicitly discussing human evaluation of LLM within healthcare contexts. The second stage involved a full-text review, emphasizing methodological detail, particularly regarding human evaluation of LLMs, and their applicability to healthcare. Due to accessibility issues, 42 articles were excluded, resulting in a final selection of 142 articles for the comprehensive literature review.