Table 3 Changes in primary and secondary outcomes from baseline to week 10 and week 20: results from a per-protocol analysis
From: The effects of a digital health intervention on patient activation in chronic kidney disease
Number of participants | Mean change from baseline (95% CI) | Mean intervention effect (95% CI)a | P value | |||
|---|---|---|---|---|---|---|
Control | Intervention | Control | Intervention | |||
Primary outcome | ||||||
PAM-13 | ||||||
Week 10 | 114 | 123 | 1.47 (95% CI: −0.81 to 3.74) | 3.58 (95% CI: 1.10 to 4.84) | 2.22 (95% CI: −0.95 to 5.39) | 0.169 |
Week 20 | 87 | 105 | 0.92 (95% CI: −1.61 to 3.45) | 4.50 (95% CI: 2.20 to 6.81) | 3.58 (95% CI: 0.16 to 7.00) | 0.041 |
Secondary outcomes | ||||||
CKD-SMKT – kidney health awareness | ||||||
Week 10 | 113 | 123 | −0.35 (95% CI: −0.47 to −0.23) | −0.54 (95% CI: −0.66 to −0.42) | −0.19 (95% CI: −0.37 to −0.02) | 0.026 |
Week 20 | 86 | 104 | −0.35 (95% CI: −0.50 to −0.20) | −0.60 (95% CI: −0.70 to −0.43) | −0.22 (95% CI: −0.42 to −0.02) | 0.030 |
CKD-SMKT – correct response | ||||||
Week 10 | 114 | 123 | 5.95 (95% CI: 2.40 to 9.50) | 12.72 (95% CI: 9.29 to 16.16) | 6.77 (95% CI: 1.83 to 11.72) | 0.007 |
Week 20 | 87 | 105 | 7.38 (95% CI: 2.15 to 12.62) | 7.18 (95% CI: 2.41 to 11.94) | −0.21 (95% CI: −7.29 to 6.87) | 0.954 |
CKD-SMKT – behaviours performed | ||||||
Week 10 | 98 | 105 | −0.66 (95% CI: −0.29 to −0.96) | −0.45 (95% CI: −0.81 to −0.16) | 0.21 (95% CI: −0.18 to 0.61) | 0.285 |
Week 20 | 73 | 86 | 0.29 (95% CI: 0.06 to 0.61) | 0.57 (95% CI: 0.27 to 0.86) | 0.28 (95%CI: -0.16 to 0.71) | 0.216 |
KSQ (frequency) | ||||||
Week 10 | 113 | 123 | 0.21 (95% CI: −0.86 to 1.27) | 0.41 (95% CI: −0.61 to 1.43) | 0.21 (95% CI: −1.27 to 1.68) | 0.783 |
Week 20 | 87 | 105 | 0.88 (95% CI: −0.46 to 2.04) | −0.34 (95% CI: −1.51 to 0.83) | −1.22 (95% CI: −2.96 to 0.52) | 0.168 |
UKDDQ | ||||||
Week 10 | 113 | 123 | −2.53 (95% CI: −3.64 to −1.42) | −1.37 (95% CI: −2.43 to −0.30) | 1.12 (95% CI: −0.37 to 2.71) | 0.136 |
Week 20 | 87 | 104 | 0.61 (95% CI: −0.57 to 1.80) | 2.57 (95% CI: 1.49 to 3.66) | 1.96 (95% CI: 0.35 to 3.57) | 0.017 |
MARS-5 | ||||||
Week 10 | 110 | 116 | 0.02 (95% CI: −0.25 to 0.29) | −0.08 (95% CI: −0.35 to 0.18) | −0.10 (95% CI: −0.48 to −0.28) | 0.613 |
Week 20 | 84 | 99 | −0.16 (95% CI: −0.49 to 0.18) | −0.02 (95% CI: −0.33 to 0.29) | 0.14 (95% CI: −0.31 to 0.59) | 0.543 |
SARC-F | ||||||
Week 10 | 114 | 123 | 0.09 (95% CI: −0.10 to 0.28) | 0.02 (95% CI: −0.17 to 0.21) | −0.07 (95% CI: −0.34 to 0.20) | 0.612 |
Week 20 | 87 | 105 | 0.20 (95% CI: −0.01 to 0.40) | −0.08 (95% CI: −0.27 to 0.11) | −0.27 (95% CI: −0.55 to 0.01) | 0.057 |
STS-60 | ||||||
Week 10 | 98 | 108 | 0.38 (95% CI: −0.76 to 1.52) | 1.52 (95% CI: 0.44 to 2.61) | 1.14 (95% CI: −0.44 to 2.72) | 0.155 |
Week 20 | 77 | 90 | 0.69 (95% CI: −0.77 to 2.15) | 3.12 (95% CI: 1.77 to 4.47) | 2.43 (95% CI: 0.43 to 4.43) | 0.018 |
