Table 5 Comparison of various metrics across different virtual cohort augmentation strategies

From: Probing the limits and capabilities of diffusion models for the anatomic editing of digital twins

Augmentation strategy

Topological violations (%)

Morphological metrics

MMD ()

COV (%, )

1-NNA (%, )

  

Prec. ()

Rec. ()

FMD ()

CD

EMD

CD

EMD

CD

EMD

Uncond + Filter

11.2

0.98

0.38

5.40

2.6

6.0

20.00

20.00

95.26

94.74

Pert. + Filter

12.2

0.98

0.92

2.11

1.19

3.95

82.00

84.00

64.11

54.21

Local. + Filter

12.0

0.96

0.90

2.94

1.16

3.96

94.00

94.00

49.47

53.69

  1. All comparison metrics were calculated using the target cohort as a reference. MMD-CD and MMD-EMD values were multiplied by 1000 and 100 respectively.